Growth Hormone (GH) and Cardiovascular System
نویسندگان
چکیده
منابع مشابه
Growth Hormone (GH) and Cardiovascular System
This review describes the positive effects of growth hormone (GH) on the cardiovascular system. We analyze why the vascular endothelium is a real internal secretion gland, whose inflammation is the first step for developing atherosclerosis, as well as the mechanisms by which GH acts on vessels improving oxidative stress imbalance and endothelial dysfunction. We also report how GH acts on corona...
متن کامل1 Title : Growth Hormone ( GH ) and Cardiovascular 2 system 3
This review describes the positive effects of growth hormone on the cardiovascular 13 system. We analyze why the vascular endothelium is a real internal secretion gland, whose 14 inflammation is the first step for developing atherosclerosis, as well as the mechanisms by which 15 GH acts on the vascular endothelium improving its dysfunction. We also report how GH acts on 16 coronary arterial dis...
متن کاملGrowth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.
GH-releasing peptide-6 (GHRP-6) is a potent GH secretagogue that releases GH by uncertain mechanisms. To assess whether GHRH is required for GH release by GHRP-6 in humans, we used the specific antagonist to GHRH (N-Ac-Tyr1,D-Arg2)GHRH(1-29)NH2 (GHRH Ant). We have previously shown that GHRH-Ant (400 microg/kg) blocked the GH response to 0.33 and 3.3 microg/kg boluses of GHRH by 95% and 81%, res...
متن کاملRole of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion.
Leptin is a hormone secreted by the adipocytes that regulates food intake and energy expenditure. It is known that growth hormone (GH) secretion is markedly influenced by body weight, being suppressed in obesity and cachexia, and recent data have demonstrated that GH release is regulated by leptin levels. Although one of the sites of action of leptin is likely to be the hypothalamus, since lept...
متن کاملComments on "growth hormone (GH)-releasing hormone and GH secretagogues in normal aging".
Comments on “Growth hormone (GH)-releasing hormone and GH secretagogues in normal aging” This issue of Clinical Interventions in Aging contains a quite interesting and informative article about a topic that is popular and also controversial among practitioners of age-management medicine. Appropriate to that controversy, Drs Hersch and Merriam (2008) have asked the question in the title of their...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms19010290